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Small Changes, Big Consequences? Assessment of the Impact of Design Changes in Microsampling Devices

Laura Boffel1, Christophe P Stove

  • 1Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent, Belgium.

Therapeutic Drug Monitoring
|December 12, 2025
PubMed
Abstract

No abstract available in PubMed .

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Effective sample preparation is crucial for accurate and reliable laboratory analysis. During this process, two significant sources of error can arise: concentration bias from improper sample splitting and contamination caused by methods used to reduce particle size, such as grinding or homogenization. Identifying and minimizing these potential errors is crucial to ensuring the validity of the analysis.
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