A Pathway for Improving Performance and Interpretation of Strain in a Pediatric Echocardiography Laboratory

Shivani Patel1,2, Nazia Husain1,2, Jennifer Acevedo1

  • 1Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.

PubMed

Insights

Implementing a structured pathway improved global longitudinal strain (GLS) reporting and accuracy in pediatric echocardiography. This ensures reliable assessment of heart function in children at risk for cardiotoxicity.

Area of Science:

  • Pediatric Cardiology
  • Cardiac Imaging
  • Echocardiography

Background:

  • Echocardiographic assessment of myocardial deformation is crucial for evaluating left ventricular systolic function in pediatric patients.
  • Accurate and reproducible strain data are essential for clinical utility in pediatric echocardiography labs.
  • This study details an institutional pathway for successful implementation of strain analysis.

Purpose of the Study:

  • To describe the institutional experience and pathway for implementing global longitudinal strain (GLS) analysis in pediatric echocardiography.
  • To improve the quality and accuracy of GLS performance and reporting in children at risk for cardiotoxicity.

Main Methods:

  • Utilized plan-do-study-act cycles from 2016 onwards, including protocol development, education, and equipment/software updates for GLS.
  • Reviewed echocardiograms from 2019-2023 for children at risk of chemotherapy-related cardiotoxicity (CTRCD).
  • Assessed the percentage of echocardiograms with performed and reported GLS, evaluating accuracy.

Main Results:

  • GLS reporting increased from 39% in 2019 to 76% in 2023; accuracy improved from 57% to 72% (p < 0.001).
  • Inaccurate GLS was attributed to poor image quality (24%), border tracing errors (45%), or both (21%).
  • Reporting of GLS improved significantly with on-cart automation, easier post-processing, and iterative education.

Conclusions:

  • Administrative, technological, and educational interventions are key to establishing consistent, high-quality GLS performance and accurate reporting in pediatric echocardiography.
  • Successful implementation pathways are vital for reliable myocardial deformation assessment in pediatric cardiology.
Abstract