Related Experiment Video
Updated: May 13, 2026
13:35
Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos
Published on: March 21, 2021
11.6K
Prevalence of Stroke-Related Sarcopenia: A Systematic Review and Meta-Analysis
Lavinia Pereira Dos Santos1, Bruna Machado Staico1, Anna Balsamão Vaz1
1Faculdade de Ciências Mêdicas de Minas Gerais, Belo Horizonte, Brazil.
Summary
Post-stroke sarcopenia is highly prevalent, affecting nearly 40% of individuals. This meta-analysis highlights significant variability in diagnosis and screening methods, underscoring the need for standardized approaches to improve patient care.
Area of Science:
- Neurology
- Gerontology
- Rehabilitation Medicine
Background:
- Sarcopenia, a loss of muscle mass and strength, negatively impacts post-stroke functionality.
- Understanding the prevalence of sarcopenia after stroke is crucial for developing targeted interventions.
- This study addresses the need for an updated meta-analysis on post-stroke sarcopenia prevalence.
Purpose of the Study:
- To conduct an up-to-date meta-analysis to investigate the prevalence of sarcopenia in individuals following a stroke.
Main Methods:
- A systematic review of multiple databases (MEDLINE, SCIELO, EMBASE, LILACS, PEDro, EBSCOHOST, AMED) and gray literature was performed.
- No date or language restrictions were applied to the search.
- Thirty-one studies totaling 7357 post-stroke individuals were included.
Main Results:
- The overall prevalence of sarcopenia diagnoses was 37.2% (moderate-quality evidence).
- Prevalence varied significantly based on diagnostic and screening methods.
- Most included studies were conducted in Asia (80.6%) and utilized the Asian Working Group of Sarcopenia criteria (58%).
Conclusions:
- High prevalence rates of post-stroke sarcopenia were observed, accompanied by considerable variability.
- Lack of consensus on sarcopenia definition, diagnostic criteria, measurement tools, and sample heterogeneity impacts results.
- Standardization of diagnostic approaches is essential for accurate prevalence assessment and effective intervention planning.
Related Concept Videos
01:27Regulation of Stroke Volume
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
01:27Pharmacodynamics in Geriatric Patients: Effects of Age
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...