Related Experiment Video
Updated: Jan 8, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Global burden of ischemic heart disease due to omega-3 deficiency: 204-country analysis, 1990-2021
Xiaozhi Chen1, Lei Chen2, Xinyue Yang3
1Department of Cardiology, National Cardiovascular Disease Regional Center for Anhui, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Aim:
This study evaluates the global burden, trends, and dietary risk factors of ischemic heart disease (IHD) from 1990 to 2021, focusing on socioeconomic and demographic variations.
Methods:
The study analyzed IHD-related disability-adjusted life years (DALYs), age-standardized rates (ASR), age-standardized mortality rates (ASMR), and fatality counts. Temporal trends were assessed using estimated annual percentage changes (EAPCs). Dietary risk factors, such as seafood omega-3 fatty acid deficiency, were evaluated in relation to the socio-demographic index (SDI).
Results:
From 1990 to 2021, DALY rates and fatalities from IHD increased globally. Omega-3 fatty acid deficiencies were identified as a significant contributor. ASMR and age-standardized death rates (ASDR) rose most notably in Central Asia and Eastern Europe. Countries with lower SDI levels faced a higher IHD burden. National trends varied, with adverse correlations between IHD burden and SDI primarily linked to dietary risks.
Conclusion:
Deficiencies in omega-3 fatty acids and other dietary risks are key factors driving global IHD patterns. Public health strategies to improve diet, particularly in low- and middle-SDI regions, are essential to reducing the IHD burden.
More Related Videos
03:35Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
Published on: December 1, 2023
09:06Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
Published on: February 20, 2019
Related Concept Videos
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Coronary Artery Disease IV: Preventive Measures
Coronary Artery Disease III: Clinical Manifestations
Coronary Artery Disease I: Introduction
Coronary Artery Disease II: Pathophysiology
Atherosclerosis III: Management