Related Experiment Video
Updated: Jan 8, 2026

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
Published on: December 18, 2016
Dissecting the difference between positive and negative brain health sentiment using X data
Piotr Religa1, Michel-Edwar Mickael2, Marzena Łazarczyk2
1Department of Medicine, Karolinska Institute, Solna, Sweden.
Introduction:
Human behavior is significantly influenced by emotions, with negative sentiments such as fear and anxiety driving various coping mechanisms, including cognitive behavioral therapy (CBT), dietary changes, and medication use. Social media platforms like X (formerly Twitter) offer valuable insights into these behaviors due to their real-time, user-generated content. While previous research has explored general sentiment on X (formerly Twitter), there has been limited focus on the reasons behind negative sentiments and the coping strategies employed, particularly in relation to brain health.
Methods:
We analyzed 390,000 X-posts tagged with #brain and #health, categorizing them into positive, negative, and neutral sentiments. We then investigate the use of CBT techniques, dietary adjustments, and specific medications across these sentiments.
Results:
Our findings reveal distinct patterns in how negative and positive sentiments are expressed and managed on social media. Negative sentiments are often linked to serious health concerns, such as COVID-19 and brain inflammation, and exhibit various cognitive distortions. These X-posts also mention coping strategies like using medications such as lorazepam and simvastatin, or consuming comfort foods like pizza. In contrast, positive sentiments emphasize resilience and improvement, with mentions of mindfulness, supplements, and medications like doxycycline and pregabalin. The study also highlights the risk of disseminating information about dietary and drug supplements that may not be suitable for public use due to serious side effects, such as Chaga mushrooms, which, despite being associated with positive sentiment, are known to cause renal failure in certain cases.
Conclusion:
Overall, the study profiles the use of positive and negative brain health sentiment of X, which underscores both the advantages and risks of using X (formerly Twitter) as a platform for sharing brain health-related information.
Related Concept Videos
Introduction to the Sign Test
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Sign Test for Matched Pairs
To conduct the sign test, we first calculate the differences in...
Traits, Mood, and Subjective Wellbeing
Neuroticism and...
Framing Effects
Regression Toward the Mean

