Stroke and associated comorbidities in Southeast Asian countries.
Aishika Datta1, Soumya Akundi1, Kaveri Wagh1
1Department of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad Gandhinagar Gujarat India.
Neuroprotection (Chichester, England)
|December 12, 2025
Summary
Stroke is a major global health issue. This review highlights how comorbidities like hypertension and hyperglycemia worsen stroke outcomes, especially in Southeast Asia due to data gaps.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- Stroke is a leading cause of death and disability globally.
- Diverse risk factors include age, sex, ethnicity, and lifestyle diseases.
- Comorbidities significantly worsen stroke outcomes and increase population burden.
Purpose of the Study:
- To review published studies on stroke comorbidities.
- To emphasize the incidence and prevalence of stroke burden in Southeast Asia.
- To address research disparities linked to insufficient demographic data on comorbidities.
Main Methods:
- Comprehensive review of published hospital-based studies.
- Analysis of data from national stroke registries.
- Focus on Southeast Asian countries and their developing economies.
Main Results:
- High stroke prevalence in Southeast Asia imposes a substantial healthcare and economic burden.
- Insufficient documentation of stroke-related comorbidities complicates management in developing nations.
- Research disparities are often linked to inadequate demographic data on comorbidities.
Conclusions:
- Understanding the association between comorbidities and stroke is crucial for effective management.
- Addressing data gaps in Southeast Asia is vital for improving stroke care and reducing burden.
- Further research is needed to elucidate the full impact of comorbidities on stroke in diverse populations.
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