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Benign Mandibular Cavity/Stafne's Bone Cyst: A Case Report and Review.
Fawzia M Butt1, Shamim M Butt2, Mark L Chindia3
1Human Anatomy University of Nairobi Nairobi Kenya.
Clinical Case Reports
|December 12, 2025
Summary
Stafne bone defect, usually asymptomatic, can mimic malignancy in high-risk patients. Surgical investigation is crucial for accurate diagnosis when symptoms are present.
Area of Science:
- Oral and Maxillofacial Surgery
- Radiology
- Oncology
Background:
- Stafne bone defect is a common, asymptomatic, radiolucent lesion in the mandibular body.
- Radiologically, it can resemble other pathologies, necessitating careful evaluation.
Purpose of the Study:
- To report a case of a symptomatic Stafne bone defect in a high-risk patient.
- To highlight the importance of surgical investigation in differentiating benign lesions from malignancy based on clinical and radiological presentation.
Main Methods:
- Case report of a patient with mandibular pain and a radiolucent lesion.
- Diagnostic imaging and subsequent surgical exploration.
Main Results:
- The patient presented with pain, unlike typical asymptomatic Stafne bone defects.
- Radiological findings were similar to a Stafne bone defect but raised suspicion due to the patient's risk profile.
- Surgical investigation confirmed the lesion was not malignant.
Conclusions:
- Symptomatic presentation of Stafne bone defect can occur, particularly in high-risk individuals.
- Surgical intervention is essential for definitive diagnosis when clinical and radiological features are concerning for malignancy.

