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Author Spotlight: Eco-Friendly Extraction of Bioactive Compounds Using Polyol-Based Microwave-Assisted Techniques
Published on: August 23, 2024
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Antioxidant Potential of Polyphenolic Compounds, Sources, Extraction, Purification and Characterization Techniques: A
Zubair Ahmad1, Abdur Rauf1, Ilkay Erdogan Orhan2
1Department of Chemistry University of Swabi Ambar Khyber Pakhtunkhwa Pakistan.
Food Science & Nutrition
|December 12, 2025
Summary
Polyphenols, plant compounds with strong antioxidant properties, are reviewed for their extraction, characterization, and applications. Research highlights their mechanisms, benefits, and challenges for wider use.
Area of Science:
- Plant Biochemistry
- Nutritional Science
- Pharmacology
Background:
- Polyphenolic compounds are abundant plant metabolites known for significant biological activities and antioxidant properties.
- Their diverse structures and functions have led to extensive research across various scientific disciplines.
Purpose of the Study:
- To provide a comprehensive review of the extraction, characterization, and application pipeline for polyphenols.
- To emphasize the mechanistic antioxidant actions and translational challenges associated with polyphenols.
Main Methods:
- Critical examination of approximately 141 studies published between 1979 and 2025.
- Evaluation of various extraction techniques (solvent, supercritical fluid, solid-phase) and characterization methods (spectroscopy, chromatography).
Main Results:
- Detailed description of polyphenol sources, structural diversity, and biological implications.
- Analysis of antioxidant mechanisms including radical scavenging, metal chelation, and signaling pathway modulation.
- Exploration of applications in nutrition, medicine, and industry, considering bioavailability and dose-dependent effects.
Conclusions:
- The review synthesizes current knowledge on polyphenols, highlighting their potential and current limitations.
- Identifies key research gaps in clinical validation, formulation, and industrial adoption for future research directions.
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