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Updated: Jan 8, 2026

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
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Bidirectional Causal Effect Between Gut Microbiota and Glioma Risk: A Systematic Review-Based Mendelian Randomization

Jiachen Wang1,2, Yilin Zhang1,2,3, Zhuang Kang1

  • 1Department of Neuro-oncology, Cancer Center, Beijing Tiantan Hospital Capital Medical University Beijing China.

Cancer Innovation
|December 12, 2025
PubMed
Summary

This study reveals a causal link between gut bacteria and glioma risk. Specific gut microbes and immune cell changes influence glioma development, offering potential diagnostic and therapeutic targets.

Keywords:
Mendelian randomizationgenome‐wide association studygliomagut microbiotaimmune cell

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