Related Experiment Video
Updated: Jan 8, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
Cost analysis in thyroid cancer clinical trials: Toward value-based oncology care
James L Rogers1, Sebastian Henostroza1, Adam Fahey1
1Vanderbilt University School of Medicine, 1161 21st Ave S # D3300, Nashville, TN, 37232, United States of America.
Background:
Clinical trials are crucial in advancing novel therapies for thyroid cancer. Given the increased cost of modern healthcare, cost considerations in clinical trials are important yet remain under-reported.
Methods:
A search of ClinicalTrials.gov identified thyroid cancer studies including cost in the trial description or as an outcome. Data collected included trial information, cost outcomes, and cost-effectiveness analyses.
Results:
Among 46 thyroid cancer-focused clinical trials, only 28 (60.8 %) mentioned cost in any capacity, of which 21 (75 %) included cost outcomes and 7 (25 %) included cost-effectiveness analyses. Overall, cost was a primary outcome in 1 (2.2 %) trial, secondary outcome in 20 (43.5 %) trials, and exploratory outcome in 7 (15.2 %) trials.
Conclusion:
The inclusion of cost analysis in thyroid cancer clinical trials is limited. Given rising cost pressures in modern healthcare systems, the low prevalence of cost endpoints and cost-effectiveness analyses underscores the need for increased awareness and investment in this domain.
More Related Videos
Related Concept Videos
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Clinical Trials: Overview
Clinical Trials
There are four phases in a clinical trial. A phase one...
Cancer Survival Analysis
Treatment Resistant Cancers
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

