Related Experiment Video
Updated: Jan 8, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Use of a Novel Physician-Modified Frozen Elephant Trunk to Manage an Acute Aortic Arch Aneurysm
Enrico Rinaldi1, Alessandro Castiglioni2, Carlotta Bugna1
1Division of Vascular Surgery, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Background:
The frozen elephant trunk (FET) technique has become a cornerstone in managing complex aortic arch disease. However, commercial FET systems may be unavailable in emergent situations, necessitating alternative solutions.
First-In-Human/Early Reports Summary:
In a 57-year-old man with an acute arch aneurysm with dissection, we replicated the FET configuration by back-table modification of a standard thoracic stent graft and combining it with a surgical graft. This novel approach, the "C-tag Endograft SanRaffaele Arrangement to Re-create a frozen Elephant trunk" (CESARE), provides a rapid, adaptable solution for emergent aortic arch repair with FET when commercial devices are unavailable.
Discussion:
The modified device was prepared in 65 minutes and was deployed under moderate hypothermic circulatory arrest, with uneventful recovery and excellent early imaging.
Novelty:
CESARE is a rapid, customizable, and widely accessible alternative to FET.
Take-Home Message:
This technique enables effective arch repair when standard FET prostheses are unavailable.
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