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Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
Published on: June 9, 2016
Principles and Key Technologies of Magnetic Particle Imaging System: A Comprehensive Review
Jiayi Zhang1,2, Yinong Cui1,2, Yuanhao Cai1,2
1School of Information Sciences and Technology, Northwest University, Xi'an, China.
Abstract:
Magnetic particle imaging (MPI) is an emerging noninvasive, ionization-free three-dimensional tracer imaging technology that achieves imaging by leveraging the nonlinear magnetization response of superparamagnetic nanoparticles. This study conducts a systematic review of the principles and key technologies of the MPI system through literature searches in databases including PubMed, Web of Science, and Google Scholar. First, this review introduces MPI's imaging principles, image reconstruction processes, and the technical characteristics of different types of MPI devices, aiming to deepen the understanding of device applications. Second, it presents the development history of three categories of MPI systems: closed-bore, open-bore, and single-sided. Finally, this review conducts a comparative analysis of the advantages and limitations of each category and discusses the future development trends and challenges of the MPI system. This review aims to provide researchers in the field with a systematic theoretical understanding of the MPI system, promote knowledge sharing, and further encourage more scientific efforts to engage in this highly promising area of molecular imaging. EVIDENCE LEVEL: 3. TECHNICAL EFFICACY: Stage 1.
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