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The Swedish National Pediatric Cataract Register (PECARE): Coexisting systemic disorders 2007-2023
David Wackerberg1,2, Jenny Gyllén1,2, Birgitte Haargaard3
1Department of Ophthalmology, Västra Götalandsregionen, Sahlgrenska University Hospital, Mölndal, Sweden.
Systemic disorders coexist in children with cataracts, particularly bilateral cases. Further research and genetic screening guidelines are recommended for pediatric cataract patients.
Area of Science:
- Ophthalmology
- Pediatrics
- Genetics
Background:
- Pediatric cataract surgery is a critical intervention.
- Understanding coexisting systemic disorders is vital for comprehensive care.
Purpose of the Study:
- To determine the frequency and types of systemic disorders in Swedish children undergoing cataract surgery.
- To analyze the association between cataract laterality and systemic disorders.
Main Methods:
- Retrospective analysis of the Swedish National Pediatric Cataract Register (PECARE) from 2007-2023.
- Inclusion of 975 children, with exclusions for specific cataract causes.
- Follow-up data at ages 1, 2, 5, and 10 years.
Main Results:
- 15.1% of 872 children had coexisting systemic disorders.
- Systemic disorders were more prevalent in bilateral cataracts (27.6%) than unilateral (4.3%).
- Prevalence was higher in children with parental consanguinity (34.4%) and lower in hereditary cataracts (15.9%).
Conclusions:
- Systemic disorders are common in pediatric cataract patients, especially with bilateral cataracts.
- Laterality and parental consanguinity influence prevalence.
- A national consensus on genetic screening for systemic disorders is necessary.
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