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Updated: May 25, 2026

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The Swedish National Pediatric Cataract Register (PECARE): Coexisting systemic disorders 2007-2023

David Wackerberg1,2, Jenny Gyllén1,2, Birgitte Haargaard3

  • 1Department of Ophthalmology, Västra Götalandsregionen, Sahlgrenska University Hospital, Mölndal, Sweden.

Acta Ophthalmologica
|December 13, 2025
PubMed

Insights

Systemic disorders coexist in children with cataracts, particularly bilateral cases. Further research and genetic screening guidelines are recommended for pediatric cataract patients.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Genetics

Background:

  • Pediatric cataract surgery is a critical intervention.
  • Understanding coexisting systemic disorders is vital for comprehensive care.

Purpose of the Study:

  • To determine the frequency and types of systemic disorders in Swedish children undergoing cataract surgery.
  • To analyze the association between cataract laterality and systemic disorders.

Main Methods:

  • Retrospective analysis of the Swedish National Pediatric Cataract Register (PECARE) from 2007-2023.
  • Inclusion of 975 children, with exclusions for specific cataract causes.
  • Follow-up data at ages 1, 2, 5, and 10 years.

Main Results:

  • 15.1% of 872 children had coexisting systemic disorders.
  • Systemic disorders were more prevalent in bilateral cataracts (27.6%) than unilateral (4.3%).
  • Prevalence was higher in children with parental consanguinity (34.4%) and lower in hereditary cataracts (15.9%).

Conclusions:

  • Systemic disorders are common in pediatric cataract patients, especially with bilateral cataracts.
  • Laterality and parental consanguinity influence prevalence.
  • A national consensus on genetic screening for systemic disorders is necessary.
Abstract

Keywords:
cataract surgerycomorbiditycongenital cataractepidemiologypaediatric cataractquality registersystemic disorders

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