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Pairwise ratio transformation of gene expression data leads to improved checkpoint response prediction in lung cancer

Jacob Pfeil1, Liqian Ma2, Hin Ching Lo2

  • 1GRC Computational Oncology, AbbVie Bay Area, 1000 Gateway Boulevard, South San Francisco, CA, 94080, USA. jacob.pfeil@abbvie.com.

BMC Bioinformatics
|December 13, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Checkpoint blockade therapyDrug response predictionFeature engineeringGene expression analysisMachine learningPrecision oncology

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