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Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
Hepatic steatosis detected on low-dose computed tomography in high-risk participants of a lung cancer screening
Asha Bonney1,2, Michelle Chua3, Diane Pascoe3,4
1Department of Respiratory and Sleep Medicine, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Abstract:
Moderate to severe hepatic steatosis was detected on low-dose computed tomography (LDCT) in 15% of participants undergoing lung cancer screening in a retrospective observational study. Almost half of participants with hepatic steatosis (21/45) were at intermediate risk of liver fibrosis, with four participants (8.9%) at high risk based on Fibrosis-4 scores. Based on current guidelines, these participants would be recommended to undergo further evaluation for liver disease. The clinical impact of moderate to severe hepatic steatosis incidentally detected on lung cancer screening LDCT requires further consideration and evaluation.
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