Related Experiment Video
Updated: Jan 8, 2026

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
Published on: September 19, 2025
Thinking outside the (ventilator) box: Enteral ventilation in humans
Heather L Clark1, Kevin W Gibbs2
1Department of Medicine, Section of Pulmonary, Critical Care, Allergy and Immunologic Disease, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Abstract:
The manuscript by Fujii et al. describes the first in-human trial testing of the safety and feasibility of intrarectal perfluorodecalin, a potential method of enteral ventilation. The investigators found that a one-time dose of perfluorodecalin was safe and tolerated without significant adverse effects in healthy men. More work is needed to demonstrate whether this compound can effectively improve oxygenation in critically ill patients.
Related Concept Videos
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Mechanical Ventilation I: Indication and Settings
Endotracheal Intubation I: Procedure
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
Respiratory Volumes and Capacities

