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Epilepsy research in 2025: sudden unexpected death in epilepsy, artifical intelligence and seizure classification
1Department of Neuroscience, The School of Translational Medicine, Monash University & Alfred Health, Melbourne, Victoria 3004, Australia.
The Lancet. Neurology
|December 13, 2025
Abstract
No abstract available in PubMed .
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01:24Epilepsy and Seizures: Overview
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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
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Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
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