Diffuse idiopathic skeletal hyperostosis in patients with prediabetes
Ayfer Altıntas1, Emre Ali Acar2, Sadettin Uslu2
1Department of Internal Medicine, Celal Bayar University School of Medicine, Manisa, Turkey.
Objective:
To investigate the frequency of diffuse idiopathic skeletal hyperostosis (DISH) in patients with prediabetes.
Material And Methods:
A total of 166 prediabetic patients were prospectively evaluated, of whom 67 with symptoms suggestive of DISH underwent thoracic and lumbar radiography. DISH was diagnosed according to Resnick and Niwayama criteria. Demographic, clinical and laboratory data were analyzed.
Results:
DISH was diagnosed in 9 patients (13.4% of symptomatic; 5.4% overall). Patients with DISH were older and more frequently hypertensive compared to those without DISH (p=0.004 and p=0.047, respectively). Other parameters such as body mass index, fasting glucose, and smoking showed higher trends in the DISH group but did not reach statistical significance.
Conclusion:
This is the first study to examine DISH in a prediabetic population. Our findings suggest a possible association between DISH and prediabetic status, although further studies are needed to confirm this relationship.
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