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Updated: Oct 13, 2026

Exploring Independent Effects of Follicle-Stimulating Hormone In Vivo in a Mouse Model
Published on: August 11, 2023
A positive feedback effect of oestradiol on LH release in the male marmoset monkey, Callithrix jacchus
Abstract:
Subcutaneous injections of oestradiol benzoate in oil, resulting in a sustained elevation of circulating oestradiol levels, induced an initial suppression of LH secretion, followed by a positive discharge of LH in castrated male and female and in intact male marmosets. Oestrogen-induced LH release (producing maximum LH concentrations 24 h after the injection) was observed in 75% of castrated males and females. A positive discharge of LH occurred in 50% of intact males 28-36 h after oestrogen administration.
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