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Related Experiment Video

Updated: Jan 8, 2026

Use of Electromagnetic Navigational Transthoracic Needle Aspiration E-TTNA for Sampling of Lung Nodules
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Tandem Needle Technique Pleural Blood Patch Embolisation for Lung Ablations.

Yan-Lin Li1,2,3, Yinji Tan4, Ruchir Shah4

  • 1Oxford Radiology Research Unit, Department of Interventional Radiology, Churchill Hospital, Oxford University Hospitals, Old Road, Headington, Oxford, OX3 7LE, UK. yan-lin.li@ouh.nhs.uk.

Cardiovascular and Interventional Radiology
|December 14, 2025
PubMed
Summary

The tandem needle technique pleural blood patch (TNT PBP) effectively prevents pneumothorax after lung ablation in high-risk patients. This minimally invasive procedure demonstrated promising safety and efficacy, with most patients avoiding chest drains and experiencing rapid recovery.

Keywords:
Interventional oncologyLung ablationLung cancerPneumothorax

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Area of Science:

  • Interventional Radiology
  • Pulmonary Medicine
  • Oncology

Background:

  • Lung ablation is a treatment for lung tumors.
  • Pneumothorax is a common complication following lung ablation.
  • Patients undergoing lung ablation often have comorbidities, increasing pneumothorax risk.

Purpose of the Study:

  • To introduce and evaluate the tandem needle technique pleural blood patch (TNT PBP) as a novel method to prevent pneumothorax after lung ablation.
  • To assess the safety and efficacy of the TNT PBP in a clinical setting.

Main Methods:

  • A retrospective case series of patients undergoing lung ablation with concomitant TNT PBP embolisation.
  • Review of patient factors, technical aspects, and clinical/radiological outcomes.
  • Definition of clinical success as successful blood patch administration and avoidance of chest drain.

Main Results:

  • 12 patients with 14 lung tumors underwent the TNT PBP procedure.
  • All patients had high pneumothorax risk due to comorbidities.
  • TNT PBP was successfully administered in all cases, with only 1 patient requiring a chest drain. Most patients were discharged the next day with no reported complications at follow-up.

Conclusions:

  • The TNT PBP technique shows a promising safety and efficacy profile for preventing pneumothorax during lung ablation.
  • Further investigation is warranted, with a randomized controlled trial (OxPET) currently underway.