Protection against HPAI-H5N8 early challenge in commercial broilers with maternal immunity: prime-boost vs. single
Wael K Elfeil1, Marwa Safwat2, Mohamed A Abaza3
1Avian and Rabbit Medicine Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt.
Avian Pathology : Journal of the W.V.P.A
|December 15, 2025
Abstract
Research Highlights:
A phylogenetic study has proven vaccine genetic match with circulating H5N8 strains.Prime-boost vaccine regimen provided 100% survival in H5N8-challenged broilers.Enhanced immunity observed in prime-boost groups, with minimal viral shedding.Single-dose groups achieved 91.7% survival and showed higher viral shedding.
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