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Published on: November 15, 2017
Enhanced-sensitivity profiling of natural products from TLC plates using a facile graphite-based LA-DART-MS platform
Xingyu Wang1, Jianxing Lv1, Yilin Chen1
1State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, The MOE Key Laboratory for Standardization of Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201210, China. linnanli@shutcm.edu.cn.
Abstract:
A graphite-assisted technique was used to enhance laser-assisted ionization TLC direct analysis in real time mass spectrometry (LA-TLC-DART-MS), improving the signal responses for flavonoids, alkaloids, volatile oils, and organic acids. When applied to citrus herbs, this method identified 14 compounds and differentiated samples from different origins, demonstrating its potential for natural product quality control.
