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Related Concept Videos

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Cirrhosis II: Pathophysiology

Cirrhosis is a progressive chronic liver injury caused by prolonged inflammation, excessive fibrotic remodeling, and impaired regeneration. Over time, repeated hepatic insults disrupt the liver’s architecture and function, leading to reduced blood flow, impaired bile drainage, and diminished metabolic capacity.Pathophysiology of cirrhosisCirrhosis arises from three main responses to chronic liver damage: inflammation, immune activation, and hepatocyte death. These processes lead to structural...
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Portal hypertension is an increase in blood pressure within the portal venous system. Normally, this pressure is less than 5 mmHg. It is considered clinically significant when it rises above 10 mmHg. At this threshold, complications from altered blood flow and venous congestion emerge.EtiologyPortal hypertension arises from conditions that impede blood flow through the liver. The most common cause is cirrhosis, in which chronic liver injury leads to fibrotic scarring. This fibrosis narrows or...

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Related Experiment Video

Updated: May 9, 2026

Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device
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Tricky Liver Case: Perihepatic Splenosis.

Ahmed Amine Dinia1, Sandy Van Nieuwenhove1, Qaid Ahmed Shagera1

  • 1Cliniques universitaires Saint Luc, Brussels, Belgium.

Journal of the Belgian Society of Radiology
|December 15, 2025
PubMed
Summary
This summary is machine-generated.

Perihepatic splenosis is a rare condition that can mimic tumors in patients without a spleen. Recognizing this splenic tissue remnant can prevent unnecessary procedures like biopsies or surgeries.

Keywords:
3D computed tomographyMRIscintigraphysplenosis

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Area of Science:

  • Medical Imaging
  • Abdominal Surgery
  • Radiology

Background:

  • Splenosis is the autotransplantation of splenic tissue after splenectomy.
  • Splenosis can occur in ectopic locations, including the subdiaphragmatic region.
  • Ectopic splenic tissue can present as a mass, potentially mimicking other pathologies.

Purpose of the Study:

  • To highlight the importance of considering perihepatic splenosis in the differential diagnosis of subdiaphragmatic masses.
  • To emphasize the characteristic imaging findings of splenosis that can aid in diagnosis.
  • To reduce the incidence of unnecessary interventions for patients with a history of splenectomy.

Main Methods:

  • Review of imaging findings in patients with confirmed perihepatic splenosis.
  • Correlation of imaging features with clinical history, particularly splenectomy.
  • Comparison of imaging characteristics of splenosis with other subdiaphragmatic masses.

Main Results:

  • Perihepatic splenosis presents as a subdiaphragmatic mass with enhancement patterns similar to normal splenic tissue on contrast-enhanced imaging.
  • Patients with splenosis typically have a history of splenectomy.
  • Characteristic imaging findings can help differentiate splenosis from neoplastic or infectious masses.

Conclusions:

  • Perihepatic splenosis should be a key consideration in patients with a history of splenectomy presenting with subdiaphragmatic masses.
  • Characteristic imaging findings can lead to a non-invasive diagnosis, avoiding further procedures.
  • Accurate diagnosis of splenosis prevents unnecessary surgical or percutaneous interventions.