Depression and Insomnia Mediate the Link Between Problematic Internet Use and Neuropathic Low Back Pain: Evidence
Ildiko Radvanyi1, Antal Tibold1, Viktoria Herczeg2
1Centre for Occupational Medicine, Medical School, University of Pécs, Pecs, Hungary.
Journal of Multidisciplinary Healthcare
|December 15, 2025
Summary
Problematic internet use (PIU) indirectly increases chronic low back pain risk, particularly its neuropathic component, by worsening depression and insomnia. Addressing these mental health and sleep issues is key for managing back pain.
Area of Science:
- Digital Health
- Pain Management
- Psychiatry
Background:
- Problematic internet use (PIU) is a growing concern with digital technology expansion.
- Understanding its impact on physical health, specifically chronic low back pain (CLBP), is crucial.
Purpose of the Study:
- To investigate the association between PIU and CLBP, including its neuropathic component.
- To identify potential mediating factors in this relationship.
Main Methods:
- A cross-sectional online survey of 550 university students aged 18-65.
- Utilized validated instruments: PIUQ, BDI-SF, AIS, and painDETECT.
- Statistical analyses included regression and mediation modeling.
Main Results:
- CLBP prevalence was 46.2%, with 12.2% experiencing neuropathic pain. PIU was present in 8.4% of participants.
- Neuropathic pain correlated with PIU, depression, and insomnia.
- PIU indirectly predicted higher painDETECT scores via depression and insomnia, not as a direct predictor.
Conclusions:
- Psychological, sleep, and lifestyle factors significantly influence CLBP.
- PIU exacerbates CLBP risk indirectly through depression and insomnia.
- Integrating screening and management of PIU, depression, and insomnia is recommended for CLBP prevention and treatment.
Related Concept Videos
Insomnia
380
Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
Multiple factors contribute...
380
CNS Depressants: Barbiturates and Benzodiazepines
1.1K
CNS depressants include drugs from the category of barbiturates and benzodiazepines. They are valuable medications for managing anxiety disorders and insomnia. Barbiturates, once used to induce and maintain sleep, have been replaced mainly by benzodiazepines due to barbiturate's toxicity, tolerance, and overdose risks. They interact with GABAA receptors, leading to sedation at low doses and potentially coma and death at higher doses. Phenobarbital, a long-acting barbiturate, possesses...
1.1K
Depressive Disorders: Etiology
412
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
412
Insufficient Sleep and Sleep Deprivation
805
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
805
Narcolepsy
463
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
463
Stress and Mental Health
564
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
564


