Association of inflammatory markers and hematological inflammatory indices in predicting pseudoexfoliation

Pseudoexfoliation syndrome (PEX) is a common age-related ocular disorder with systemic inflammatory implications. This cross-sectional study investigated the role of hematological indices-NLR, PLR, dNLR, RDW, SII, SIRI and PIV-in 195 PEX patients and 195 controls. All markers, including novel indices like SII and SIRI, were significantly elevated in PEX (p < 0.05). RDW was also higher, indicating oxidative stress and systemic involvement. These indices may serve as accessible, cost-effective predictors of PEX-related inflammation.