Management of Hyperlipidaemia using KNEA: A case report

Nikil Niva J1, Hema Nandhini Devi V2, Sridevi L3

  • 1Department of Outpatient, Siddha Clinical Research Unit, Central Council for Research in Siddha, Safdarjung Hospital, New Delhi, India.

Bioinformation
|December 15, 2025
PubMed

Insights

This case report highlights the successful management of hyperlipidemia using Siddha medications, KNEA. The treatment significantly reduced total cholesterol and LDL-C while increasing HDL-C levels, demonstrating a novel therapeutic approach.

Area of Science:

  • Integrative Medicine
  • Cardiovascular Health
  • Traditional Siddha Medicine

Background:

  • Hyperlipidemia significantly elevates the risk of atherosclerotic cardiovascular disease (ASCVD) and stroke.
  • Dyslipidemia is a primary contributor to cardiovascular diseases.
  • Siddha medicine offers potential therapeutic interventions for managing lipid disorders.

Purpose of the Study:

  • To present a case study on the efficacy of Siddha therapeutic regimens KNEA in managing hyperlipidemia.
  • To evaluate the impact of KNEA on key lipid profile parameters.

Main Methods:

  • A single-patient case report detailing the administration of Siddha medications KNEA.
  • Monitoring of lipid profile, including total cholesterol (TC), LDL-C, and HDL-C levels before and after treatment.

Main Results:

  • Successful reduction in total cholesterol from 205 mg/dL to 27 mg/dL (a decrease of 178 mg/dL).
  • Significant decrease in LDL-C from 127 mg/dL to 19 mg/dL (a reduction of 108 mg/dL).
  • Improvement in HDL-C levels, increasing from 33 mg/dL to 42 mg/dL.

Conclusions:

  • The Siddha therapeutic regimen KNEA demonstrated significant antihyperlipidemic effects in this case.
  • KNEA possesses potential hepatoprotective, antioxidant, and nephroprotective properties beneficial in hyperlipidemia management.
  • This case suggests KNEA as a viable complementary therapy for hyperlipidemia within the Siddha medical system.

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