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In situ Compressive Loading and Correlative Noninvasive Imaging of the Bone-periodontal Ligament-tooth Fibrous Joint

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Analyzing stability parameters for assessing immediate and early loading of implants.

Sachin B Mangalekar¹, Rohit Sharma², Mohammad Jalaluddin³

¹Department of Periodontology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Wanlesswadi, Sangli-416414, Maharashtra, India.

|December 15, 2025

Summary

Immediate and early dental implant loading offers faster treatment. Resonance Frequency Analysis (ISQ) and insertion torque reliably indicate when implants are stable enough for safe loading, ensuring successful osseointegration.

Keywords:

ISQ Implant stability early loading immediate loading,insertion torque osseointegration resonance frequency analysis

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Last Updated: Jul 16, 2026

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Area of Science:

Dentistry
Biomaterials Science
Orthodontics

Background:

Immediate and early loading protocols for dental implants can reduce treatment duration and improve patient satisfaction.
Successful loading depends critically on achieving adequate primary implant stability and promoting early osseointegration.
Assessing implant stability is crucial for determining appropriate loading times to prevent complications.

Purpose of the Study:

To compare implant stability parameters for guiding immediate versus early loading protocols in single posterior mandibular implants.
To evaluate the reliability of Resonance Frequency Analysis (ISQ) and insertion torque in decision-making for implant loading.
To assess marginal bone loss associated with different loading protocols.

Main Methods:

A clinical trial involving 40 patients requiring single posterior mandibular implants.
Measurement of implant stability using Resonance Frequency Analysis (ISQ) and Periotest values (PTV) at placement, 3 weeks, and 3 months.
Recording of insertion torque and radiographic assessment of marginal bone loss.

Main Results:

Both immediate and early loading groups demonstrated progressive ISQ improvement over time.
Minimal marginal bone loss was observed in both loading groups.
No statistically significant differences in ISQ, PTV, or bone loss were found between immediate and early loading protocols.

Conclusions:

ISQ and insertion torque are dependable indicators for making safe loading decisions in dental implant therapy.
Both immediate and early loading protocols can be successfully implemented when guided by appropriate stability measurements.
Further research can explore long-term outcomes and patient-reported measures.