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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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Left Atrial Epithelioid Angiosarcoma Presenting As Recurrent Stroke: A Case Report

Yoshimi Tamura1, Tadashi Kitamura2, Masaomi Fukuzumi1

  • 1Cardiovascular Surgery, Kitasato University School of Medicine, Sagamihara, JPN.

Cureus
|December 15, 2025
PubMed

A 74-year-old man presented with recurrent cerebellar infarction and progressive anemia. The workup revealed a small jejunal tumor and a mobile mass in the left atrium. Urgent minimally invasive cardiac surgery was performed, and histopathology confirmed epithelioid angiosarcoma. Subsequent small bowel resection revealed a similar tumor. Despite chemotherapy and radiotherapy, bone metastases progressed, and the patient succumbed to the disease eight months postoperatively. The cardiac tumor was smaller than typically reported, suggesting early detection prompted by embolic events. Nevertheless, the clinical course was aggressive, highlighting the high malignancy of epithelioid angiosarcoma and the limited effectiveness of current therapies. Accumulation of further clinical experience is essential to improve outcomes in this rare cardiac tumor.

Keywords:
cardiac angiosarcomacardiac tumorcerebral infarctionepithelioid angiosarcomaminimally invasive cardiac surgery

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