Related Experiment Video
Updated: Jun 24, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
A Rare Presentation of Diffuse Large B-Cell Lymphoma as a Gastric Outlet Obstruction With Complete Resolution After
Antony J Arumairaj1, Yamama Al-Khazraji2, Sajan Acharya3
1Internal Medicine/Section of Pulmonary Critical Care Medicine, Wake Forest University School of Medicine, Winston-Salem, USA.
None:
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma (NHL), accounting for approximately one-third of all cases. We report a case of DLBCL presenting as gastric outlet obstruction (GOO) with complete resolution of obstruction after chemotherapy without any surgical intervention. A 58-year-old man presented with an inability to tolerate oral intake, bilious vomiting, abdominal discomfort, and unintentional weight loss. Computed tomography (CT) of the abdomen and pelvis revealed large infiltrating retroperitoneal and mesenteric masses with extensive adenopathy. Conservative management of GOO was initiated, including gastric decompression using a nasogastric tube and intravenous fluid hydration. A para-aortic lymph node biopsy confirmed the diagnosis of DLBCL. Following the first cycle of chemotherapy, the patient showed remarkable improvement. A repeat CT scan of the abdomen demonstrated complete resolution of GOO. Gastric outlet obstruction secondary to DLBCL is a rare complication. Complete resolution of GOO with radiological evidence following chemotherapy alone, without surgical intervention, is rarely reported.
More Related Videos
Related Concept Videos
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease

