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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

220
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
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Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

253
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
253
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

373
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
373
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

429
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
429
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

371
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
371
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

380
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
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Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
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Rethinking Operability in Large VSD: The Diastolic Pulmonary Shunt Index (DiPSI) and a Probabilistic Perspective.

Saurabh Kumar Gupta1, Shyam S Kothari1,2

  • 1Department of Cardiology Cardiothoracic Centre, All India Institute of Medical Sciences New Delhi India.

Pulmonary Circulation
|December 15, 2025
PubMed
Summary
This summary is machine-generated.

A new index, the Diastolic Pulmonary Shunt Index (DiPSI), may improve operability assessments for ventricular septal defects (VSD) with pulmonary arterial hypertension (PAH). DiPSI offers a more nuanced evaluation than the current pulmonary vascular resistance index (PVRI) alone.

Area of Science:

  • Cardiology
  • Pulmonary Hypertension
  • Pediatric Cardiac Surgery

Background:

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  • Assessing operability in late-presenting ventricular septal defects (VSD) with pulmonary arterial hypertension (PAH) is challenging.
  • The pulmonary vascular resistance index (PVRI) is the primary metric but has limitations.
  • Some patients with high PVRI have good outcomes, while others with lower PVRI experience PAH recurrence.