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Predictive Biomarkers: A New Frontier in Bespoke Aesthetic Dermatology
Aesthetic Surgery Journal. Open Forum
|December 15, 2025
Summary
Biomarkers and biological hallmarks can identify patients at risk for complications from aesthetic dermatology procedures. This approach enables personalized cosmetic care, moving towards predictive and preventive models for safer, precise, and lasting results.
Area of Science:
- Aesthetic Dermatology
- Biomarkers and Hallmarks
- Personalized Medicine
Background:
- Aesthetic dermatology increasingly uses advanced injectable and energy-based treatments.
- Patient complications like granulomas and hyperpigmentation arise from biological variability.
- Current decision-making requires better biological insights for patient safety.
Purpose of the Study:
- To explore the role of biomarkers and hallmarks in predicting patient risk for aesthetic procedure complications.
- To discuss practical applications and the potential of artificial intelligence in interpreting biological data.
- To advocate for a shift towards biologically informed, predictive, and preventive aesthetic care.
Main Methods:
- Review and commentary on the application of biomarkers and hallmarks in aesthetic dermatology.
- Discussion of real-world applications, including tape stripping for molecular profiling.
- Exploration of artificial intelligence for analyzing complex biological signatures.
Main Results:
- Biomarkers and hallmarks can identify interindividual biological variability relevant to treatment outcomes.
- Tape stripping offers a practical method for molecular patient profiling.
- Artificial intelligence holds potential for interpreting intricate biological data for personalized care.
Conclusions:
- Integrating biomarkers and hallmarks can enhance safety and precision in aesthetic dermatology.
- A biologically informed approach facilitates a transition to predictive and preventive cosmetic care.
- Personalization based on skin biology promises safer, more durable aesthetic results.
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