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Assessment and Non-pharmacological Management of Chronic Pain in Pediatric Cancer Survivors: Current Practices and

Lauren Hayes1,2, Jacqueline M Pabis3,4, Megan Millmann3,4

  • 1Norton Children's Medical Group, Louisville, KY, USA. Lauren.Hayes@louisville.edu.

Current Pain and Headache Reports
|December 15, 2025
PubMed

Insights

Non-pharmacological interventions show promise for managing chronic pain in pediatric cancer survivors. Research highlights biopsychosocial assessments and therapies like physical activity and biofeedback for improved outcomes.

Area of Science:

  • Oncology
  • Pain Management
  • Pediatrics

Background:

  • Chronic pain is a significant and disabling long-term effect in pediatric cancer survivors.
  • Pain management in this population is complex, requiring comprehensive assessment to guide effective treatment.

Purpose of the Study:

  • To review less invasive, non-pharmacological interventions for chronic pain in pediatric cancer survivors.
  • To identify current assessment strategies that guide these interventions.

Main Methods:

  • Review of recent research on pain assessment and non-pharmacological interventions.
  • Analysis of studies utilizing validated measures (e.g., PROMIS) and screeners for biopsychosocial pain assessment.
  • Evaluation of preliminary findings for physical activity and biofeedback interventions.

Main Results:

  • Biopsychosocial pain assessment using validated measures and screeners is effective in pediatric cancer survivors.
  • Preliminary studies indicate positive outcomes for physical activity and biofeedback interventions.
  • Advances in pain management are promising, but further research is needed.

Conclusions:

  • Comprehensive biopsychosocial pain assessments and tailored treatments are crucial for pediatric cancer survivors.
  • Further research should explore interventions like hypnosis in this population.
  • Refining identification and treatment strategies for chronic pain in survivors is essential.
Abstract

Keywords:
AssessmentChronic painNon-pharmacological managementPediatric cancerSurvivorship

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