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Should We Re-Instrument the Originally Fused Level in ACDF Revision for Adjacent Segment Disease?: A Quality Outcomes
James F Bathon1,2, Omar Zakieh1, Claudia Davidson3
1Department of Orthopedic Surgery, Vanderbilt University Medical Center, Nashville, TN.
Spine
|December 15, 2025
Summary
Revision ACDF surgery outcomes show re-instrumentation increases perioperative risks without improving patient outcomes. Consider conservative single-level revision to minimize complications.
Area of Science:
- Spine surgery
- Orthopedics
- Neurosurgery
Background:
- Adjacent segment disease (ASD) is a common complication after anterior cervical discectomy and fusion (ACDF).
- Re-instrumentation of the original fused segment offers greater biomechanical stability.
- Limited research compares outcomes of re-instrumentation versus adjacent segment fusion in revision ACDF.
Purpose of the Study:
- To compare perioperative variables, patient-reported outcomes, and reoperation rates.
- Investigate outcomes between re-instrumentation of the original fused level and fusion of the adjacent segment alone in revision ACDF.
Main Methods:
- Retrospective cohort study of revision ACDF patients from the Quality Outcome Database.
- Primary exposure: re-instrumentation of the original segment.
- Outcomes assessed: perioperative variables, reoperation rates, and PROMs (pain, NDI, EQ-5D, mJOA) at various time points.
Main Results:
- Re-instrumentation group had higher blood loss, operative time, and hospital stay.
- No significant differences in neck/arm pain, NDI, or mJOA scores between groups at 3, 12, or 24 months.
- Reoperation rates at 3 and 12 months were comparable between the two groups.
Conclusions:
- Comparable PROMs and reoperation rates suggest avoiding re-instrumentation when feasible.
- Opting for conservative single-level revision may minimize risks associated with increased perioperative complications.
- Surgeons should consider conservative approaches to reduce blood loss, operative time, and length of stay.
