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The Risk of Developing Periampullary Tumors After Cholecystectomy: A Systematic Review and Meta-analysis

Hasan Al-Obaidi1, Nooraldin Merza2, Mustafa Al-Obaidi3

  • 1Department of Hepatology and Gastroenterology, University of Toledo, Toledo, OH.

Journal of Clinical Gastroenterology
|December 15, 2025
PubMed
Summary

Cholecystectomy (gallbladder removal) may increase the risk of developing periampullary tumors (PTs). This meta-analysis found a statistically significant elevated hazard rate for PTs post-surgery, suggesting a potential link requiring further investigation.

Keywords:
cholecystectomyperiampullary tumors (PTs)

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