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Updated: Jan 8, 2026

Assessment of Physical Activity Intensity with Accelerometers and Oxygen Consumption
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Assessment of Physical Activity Intensity with Accelerometers and Oxygen Consumption

Published on: June 20, 2025

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Accelerometer-Derived Rest-Activity Rhythm Amplitude, Genetic Predisposition, and the Risk of Ischemic Heart Disease:

Lele Wang1, Juying Zhang1, Xiong Xiao1

  • 1West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.

Journal of Medical Internet Research
|December 15, 2025
PubMed
Summary

Disrupted rest-activity rhythm amplitude (RARA) is linked to a higher risk of ischemic heart disease (IHD). This association appears independent of genetic predisposition, suggesting RARA is significant for IHD prevention.

Keywords:
Mendelian randomizationgenetic predispositionischemic heart diseasephysical activityrest-activity rhythm amplitude

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