Related Experiment Video
Updated: May 5, 2026

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography
Published on: May 26, 2015
Depolarization-Based Multimodal Optical Imaging of Carious Lesions
Julia Grundmann1,2, Christian Hannig1, Svea Steuer3
1TU Dresden, Faculty of Medicine Carl Gustav Carus, Policlinic of Operative Dentistry, Periodontology and Pediatric Dentistry, Dresden, Germany.
Abstract:
A comprehensive image catalog from an in vitro investigation of teeth with occlusal carious lesions is provided. The aim was to visualize carious lesions using various imaging techniques in order to present different stages of caries progression and to provide reference data for the development and validation of polarization-sensitive optical coherence tomography (PS-OCT) as a non-ionizing diagnostic method for dental caries. The study covers a variety of approaches, bridging the gap from basic histopathological analysis of thin sections to future optical imaging of occlusal carious lesions in vivo. All measurements were performed to support the interpretation and validation of PS-OCT imaging based on the degree of polarization (DOP).

