Related Experiment Video
Updated: Jan 8, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Atraumatic grade five renal injury
Phaedra Rampersad1, Silas Webb2, David Connor1
1Emergency Medicine, Chelsea and Westminster Healthcare NHS Trust, London, England, UK.
Abstract:
A young female in her 30s presented with right lumbar and flank pain after performing deadlift exercises at the gym. Whilst initially thought to have a presentation of acute musculoskeletal back pain, she had two unexpected syncopal episodes whilst in the waiting room. She went on to be diagnosed with an unexpected grade V renal injury and active retroperitoneal haemorrhage. She became haemodynamically unstable and was treated using the hospital major haemorrhage protocol. The patient was ultimately transferred to a tertiary centre, where she underwent renal artery embolisation successfully.Atraumatic renal injury is rare and has only been described in a few case reports. Classic signs, as well as point-of-care ultrasound, are sometimes unreliable for diagnosing retroperitoneal haemorrhage. Therefore, emergency physicians must keep renal injuries within the differential diagnosis of flank pain even in the absence of overt trauma.
Related Concept Videos
Acute Kidney Injury II: Pathophysiology
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Kidney Injury III: Clinical Manifestations
Acute Kidney Injury I: Introduction
Acute Kidney Injury V: Interprofessional Care
Acute Kidney Injury VI: Nursing Management

