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Perspective in radiofrequency ablation for benign thyroid nodules: A perspective.
Zhuan-Ning Han1, Xu-Ping Shen2, Rong-Rong Wang3
1Department of Ultrasound, The Second Affiliated Hospital of Xi'an Medical College, Xi'an, China.
Medicine
|December 16, 2025
Summary
Radiofrequency ablation (RFA) offers a minimally invasive treatment for benign thyroid nodules (BTNs), reducing volume and complications. Further research will refine RFA
Area of Science:
- Endocrinology
- Minimally Invasive Surgery
Background:
- Benign thyroid nodules (BTNs) are common, often requiring intervention.
- Traditional surgical management carries risks of trauma and complications.
Purpose of the Study:
- To review the efficacy and advancements of radiofrequency ablation (RFA) for BTNs.
- To identify current limitations and future research directions for RFA in BTN management.
Main Methods:
- Review of existing empirical evidence and technological advancements in RFA for BTNs.
- Analysis of RFA's impact on nodule volume and thyroid function.
Main Results:
- RFA effectively reduces BTN volume while preserving thyroid parenchyma.
- Ultrasound guidance enhances RFA precision and safety.
- RFA offers faster recovery and fewer complications than surgery.
Conclusions:
- RFA is a safe and effective minimally invasive treatment for BTNs.
- Further research is needed to optimize patient selection and long-term outcomes.
- Advancements position RFA as a mainstream treatment option for BTNs.

