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A giant peritoneal loose body: A case report and updated literature review and data synthesis
Guo-Le Nie1,2, Shicheng Chu1,2, Song Geng1,2
1Department of Colorectal Hernia Surgery, Binzhou Medical University Hospital, Binzhou, China.
Abstract:
We report an 80-year-old male with a nodular fibrous pseudotumor (NFP), a rare benign tumor typically linked to trauma, surgery, or inflammation. Unusually, it presented as a mobile peritoneal loose body (PLB) despite no relevant abdominal history. Imaging showed a well-defined oval mass (70 × 63 mm). Pathological examination confirmed NFP, showing hyalinized collagen and fibroblast proliferation without atypia. This is the first NFP presenting as a PLB at our institution. The patient underwent successful laparoscopic resection with no recurrence during follow-up. This case highlights that: NFP can mimic mobile intraperitoneal lesions, requiring distinction from malignancy; pathological confirmation is essential due to overlapping computed tomography features with metastases; and the PLB presentation expands the known etiological spectrum beyond classical triggers. NFP should be considered in the differential diagnosis of peritoneal nodules, especially in atypical scenarios.
Insights
This case study details a rare nodular fibrous pseudotumor (NFP) presenting as a mobile peritoneal loose body (PLB). It highlights NFPs mimicking intraperitoneal lesions and expands their known causes.
Area of Science:
- Gastroenterology
- Surgical Pathology
Background:
- Nodular fibrous pseudotumor (NFP) is a rare benign neoplasm.
- NFPs are typically associated with trauma, surgery, or inflammation.
- Mobile peritoneal loose bodies (PLBs) are uncommon intraperitoneal findings.
Purpose of the Study:
- To report a unique case of NFP presenting as a PLB.
- To discuss the diagnostic challenges and implications of this presentation.
- To expand the understanding of NFP etiology.
Main Methods:
- Case report of an 80-year-old male patient.
- Imaging studies (CT scan) for mass characterization.
- Histopathological examination for definitive diagnosis.
- Laparoscopic resection and follow-up.
Main Results:
- An 80-year-old male presented with an asymptomatic mobile peritoneal loose body.
- Imaging revealed a well-defined oval mass.
- Pathology confirmed nodular fibrous pseudotumor (NFP) with hyalinized collagen and fibroblast proliferation.
- Successful laparoscopic resection was performed with no recurrence.
Conclusions:
- NFP can present atypically as a mobile peritoneal loose body, mimicking other intraperitoneal lesions.
- Distinguishing NFP from malignancy is crucial, necessitating pathological confirmation.
- This case broadens the etiological spectrum of PLBs beyond typical triggers.
