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Lactate/Albumin Ratio vs. NEWS-Lactate in Sepsis-Induced Acute Kidney Injury Prognosis; Comment on Le Xuan at al.
Qing-Bao Jiang1, Guo-Ming Zhang2
1Department of Laboratory Medicine, Daqing Hospital of Traditional Chinese Medicine, Daqing 163311, Heilongjiang, People's Republic of China.
Abstract:
A study by Le Xuan et al. suggested that the lactate/albumin ratio (LAR) may aid in predicting sepsis-associated acute kidney injury. However, overlapping receiver operating characteristic (ROC) curve confidence intervals, creatinine-only acute kidney injury (AKI) definitions, and single-point biomarker assessments limit interpretation. Given its single-centre retrospective design, broader validation with dynamic biomarkers and kidney-specific comparators is needed before the LAR can be integrated into sepsis risk stratification.
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