Related Experiment Video
Updated: Jan 8, 2026

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
A Rare Metastatic Fibrous Tumor: Review of Literature With a Case Report
Gowri Swaminathan1, Jonathan Muratori1, Faateh Rauf1
1Department of Medicine, Icahn School of Medicine at Mount Sinai, NYC Health and Hospitals, Queens, New York.
Abstract:
Solitary fibrous tumors (SFTs) can be either localized or metastatic. We present a rare case of a 69-year-old patient with a metastatic solitary fibrous tumor in uncommon anatomical locations, treated with a short course of pazopanib. While surgical resection remains the primary treatment for localized SFT, chemotherapy has been used for advanced cases. Our unique case highlights the need for more research into treatment options to improve patient outcomes. Since both benign and malignant SFTs can metastasize, mortality is mainly due to thoracic metastases; further studies are needed to understand the prognostic factors that influence disease spread versus local growth.
Insights
This study reports a rare case of metastatic solitary fibrous tumor (SFT) in unusual locations, treated with pazopanib. Further research is needed to improve outcomes for advanced SFT cases.
Area of Science:
- Oncology
- Pathology
Background:
- Solitary fibrous tumors (SFTs) are neoplasms with potential for localized or metastatic spread.
- While localized SFTs are typically managed with surgical resection, advanced or metastatic cases present treatment challenges.
More Related Videos
13:41Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
Published on: January 13, 2023
09:01Cancer-Associated Fibroblasts from Mouse Mammary Tumors as Tools for Molecular and Computational Studies
Published on: July 3, 2025