Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Atomic Force Microscopy

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...

Overview of Microscopy Techniques

Overview of Microscopy Techniques

The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...

Atomic Absorption Spectroscopy: Atomization Methods

Atomic Absorption Spectroscopy: Atomization Methods

Atomic Absorption Spectroscopy (AAS) atomizes samples through flame atomization or electrothermal atomization. Flame atomization typically involves a nebulizer and spray chamber assembly to combine the sample with a fuel–oxidant mixture, creating a fine aerosol mist that enters a burner. Typically, the fuel and oxidant are combined in an approximately stoichiometric ratio. However, for atoms that are easily oxidized, a fuel-rich mixture may be more advantageous. Only about 5% of the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A GaN/HfZrCO<sub>2</sub> heterojunction with excellent photoresponse and superior hydrogen evolution reaction performance.

Physical chemistry chemical physics : PCCP·2026

Same author

Falcon Vision-Inspired Ultrafast Traffic Obstacle Avoidance Based on 2D Edge-Rich van der Waals Heterostructures.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

Exploring partially reduced CeO <math><msub><mi> </mi> <mn>2</mn></msub></math> (111) surface at the atomic scale using scanning probe microscopy.

Science and technology of advanced materials·2025

Same author

A metaverse laboratory setup for interactive atom visualization and manipulation with scanning probe microscopy.

Scientific reports·2025

Same author

Early prediction of preeclampsia from clinical, multi-omics and laboratory data using random forest model.

BMC pregnancy and childbirth·2025

Same author

Structural insights into CDF1 accumulation on the CONSTANS promoter via a plant-specific DNA-binding domain.

Nature plants·2025

Same journal

Higher-Order Clustering of Receptors Real-Time Projected by Plasmon-ruler on the Single Live Cell.

Nano letters·2026

Same journal

Achieving Fermi-Level Depinning and Ideal Metal Contact in <i>β</i>-Ga<sub>2</sub>O<sub>3</sub> Devices via MXene Integration.

Nano letters·2026

Same journal

AI-Assisted Electron Microscopy in Structure-Performance Analysis of Advanced Catalysts: From Atomic Resolution to Statistical Significance.

Nano letters·2026

Same journal

Electrically Switchable Ultraslow Dispersionless Polaritons via Twist Engineering in van der Waals Heterostructures.

Nano letters·2026

Same journal

Correction to "Ultrasonication-Triggered Ubiquitous Assembly of Magnetic Janus Amphiphilic Nanoparticles in Cancer Theranostic Applications".

Nano letters·2026

Same journal

Tunable Proximity Valley Splitting Via Interfacial Exchange Pinning in WSe<sub>2</sub>-CrBr<sub>3</sub>-CrPS<sub>4</sub> Heterostructures.

Nano letters·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 8, 2026

Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface

Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface

Published on: October 2, 2016

Integrated AI Framework for Room-Temperature Atom Manipulation in Scanning Probe Microscopy.

Junya Okuyama¹, Zhuo Diao¹, Hayato Yamashita¹

¹Graduate School of Engineering Science, The University of Osaka, 1-3 Machikaneyama, Toyonaka, Osaka 560-8531, Japan.

|December 16, 2025

Summary

This summary is machine-generated.

This study introduces an artificial intelligence (AI) framework for autonomous atom manipulation of silver atoms on silicon surfaces at room temperature. The AI system successfully performed complex atomic manipulations for over 25 hours without human intervention.

Keywords:

atom manipulation automated SPM deep learning room temperature surface dynamics

More Related Videos

Author Spotlight: Introduction to Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays

Author Spotlight: Introduction to Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays

Published on: June 13, 2023

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Published on: December 20, 2016

Related Experiment Videos

Last Updated: Jan 8, 2026

Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface

Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface

Published on: October 2, 2016

Author Spotlight: Introduction to Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays

Author Spotlight: Introduction to Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays

Published on: June 13, 2023

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Published on: December 20, 2016

Area of Science:

Materials Science
Artificial Intelligence
Surface Science

Background:

Atom manipulation is crucial for atomic-scale fabrication.
Current methods often require manual control and specific conditions.
Developing autonomous systems can enhance efficiency and precision.

Purpose of the Study:

To develop an integrated AI framework for autonomous atom manipulation.
To enable room-temperature operation for silver atom manipulation on Si(111)-(7 × 7).
To establish a foundation for high-throughput atomic-scale fabrication.

Main Methods:

An integrated AI framework combining four machine learning models.
Models evaluate tip/surface conditions, detect silver atoms, locate defect-free half-unit cells (HUCs), and assess manipulation parameters.
Autonomous scanning tunneling microscopy (STM) operation including thermal drift correction and probe conditioning.

Main Results:

Demonstrated robust, long-term autonomous operation for over 25 hours.
Successfully executed lateral and vertical silver atom transfers between HUCs.
Achieved AI-driven autonomous atomic manipulation at room temperature.

Conclusions:

The integrated AI framework shows feasibility for autonomous atomic manipulation at room temperature.
Tip stability remains a challenge impacting success rates.
This work lays the groundwork for future high-throughput atomic-scale fabrication using AI.