![Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F3777.jpg&w=3840&q=50)
Rosai-Dorfman Disease Involving Thymus and Aorta Revealed by 18 F-FDG PET/CT
Mengfang Qi1, Junjun Cheng, Hongyuan Dai
1Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, China.
Clinical Nuclear Medicine
|December 16, 2025
Abstract:
Rosai-Dorfman disease (RDD) is a rare non-Langerhans cell histiocytosis primarily involving lymph nodes, with occasional extranodal manifestations. Thymic and aortic involvement is exceptionally uncommon. We reported a case of a 33-year-old woman presenting with a mediastinal mass on 18 F-FDG PET/CT, revealing intense metabolic activity in the thymic region and thoracic aorta. Histopathology confirmed the diagnosis of RDD.
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