[Impact of motor impairment and oro-gastric issues on the growth of children and adolescents with cerebral palsy]
View abstract on PubMed
Summary
This summary is machine-generated.Children and adolescents with cerebral palsy (CP) experiencing orogastric issues and severe functional limitations face higher risks of growth impairment, including being underweight and stunted.
Area Of Science
- Pediatric Nutrition
- Neurology
- Developmental Pediatrics
Background
- Children and adolescents (CA) with cerebral palsy (CP) frequently encounter growth challenges and gastrointestinal problems, influenced by their functional capabilities.
- Orogastric disorders and varying functional severities significantly impact nutritional status in this population.
Purpose Of The Study
- To investigate the relationship between orogastric disorders, functional classifications (GMFCS, EDACS), and anthropometric parameters in Argentinian children and adolescents with CP.
- To identify risk factors for growth impairment in pediatric CP patients.
Main Methods
- An observational, analytical, cross-sectional study involving sequential sampling of 199 participants aged 1-18 years.
- Assessment of nutritional status using WHO Anthro Plus software, alongside analysis of orogastric disorders, Gross Motor Function Classification System (GMFCS), and Eating and Drinking Ability Classification System (EDACS).
- Statistical analysis included Mann-Whitney and t-tests, with multiple logistic regression models (MLR) for variables with p < 0.05.
Main Results
- Significant differences in P/E, T/E, and BMI/E z-scores were found in CA with CP who had orogastric problems and more severe functional impairments.
- Higher chances of being underweight were associated with severe EDACS levels (8.77 times) and severe GMFCS (3.36 times).
- Increased likelihood of stunting was linked to severe GMFCS (2.63 times) and severe EDACS (7.93 times).
Conclusions
- Orogastric disorders and severe functional limitations in children and adolescents with CP are associated with significant growth impairment.
- These factors increase the risk of stunting and being underweight in pediatric CP patients, highlighting the need for targeted interventions.
Related Concept Videos
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...

