Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Standards of Care II01:19

Standards of Care II

1.0K
Nurses bear specific legal responsibilities under several federal statutes, including:
1.0K
Nursing Ethical Principles II01:27

Nursing Ethical Principles II

2.0K
Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
2.0K
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

209
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
209
Standards of Care I01:22

Standards of Care I

1.0K
Federal statutes profoundly impact nursing practice, providing critical guidelines to ensure patient care is equitable, accessible, and of the highest quality. The following laws address distinct aspects of healthcare provision and patient rights:
1.0K
Ethical Issues01:27

Ethical Issues

2.0K
Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
2.0K
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

175
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
175

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Metastatic Colorectal Cancer as a Chronic Disease: Twelve-Year Survival After Initially Unresectable Bilobar Liver Metastases.

Cureus·2026
Same author

Uncemented total hip arthroplasty in patients with systemic malignancy without skeletal involvement: A retrospective case series.

Journal of clinical orthopaedics and trauma·2025
Same author

Geochemistry and contamination metrics of the tropical agricultural soils in Karuvannur Basin, India, with special reference to environmental sustainability.

Environmental geochemistry and health·2025
Same author

Stunting and Its Determinants among Under-five Children in East Khasi Hills District, Meghalaya.

Indian journal of public health·2025
Same author

From Hub to Horizon: A Rural Medicine Revolution With Project ECHO.

Academic medicine : journal of the Association of American Medical Colleges·2025
Same author

Defying the Odds: Small Cell Lung Cancer with Essential Thrombocythemia and Secondary Cancers.

Cureus·2025

Related Experiment Video

Updated: Jan 8, 2026

Oral Health Assessment by Lay Personnel for Older Adults
08:47

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

13.4K

Critical assessment of geriatric oncology guidelines based on the AGREE II tool.

Gayathri Nair1, Cailyn H Livingstone2, Jonathon W Vundum3

  • 1Medical Oncology Fellow, Chris O'Brien Lifehouse, NSW, Australia.

Journal of Geriatric Oncology
|December 16, 2025
PubMed
Summary

This study evaluated geriatric oncology guidelines, finding variability in quality and applicability. Future guidelines need improved stakeholder involvement and methodological rigor for better cancer care in older adults.

Keywords:
AGREE IIASCOCancer careClinical guidelinesGeriatric oncologyNCCNOlder cancer patientsSoFOG

More Related Videos

Assessing Specificity of Anticancer Drugs In Vitro
09:39

Assessing Specificity of Anticancer Drugs In Vitro

Published on: March 23, 2016

9.8K
Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

7.6K

Related Experiment Videos

Last Updated: Jan 8, 2026

Oral Health Assessment by Lay Personnel for Older Adults
08:47

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

13.4K
Assessing Specificity of Anticancer Drugs In Vitro
09:39

Assessing Specificity of Anticancer Drugs In Vitro

Published on: March 23, 2016

9.8K
Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

7.6K

Area of Science:

  • Geriatric Oncology
  • Clinical Practice Guidelines
  • Evidence-Based Medicine

Background:

  • The global population is aging, leading to a higher cancer burden in older adults.
  • Older adults are underrepresented in clinical research, limiting the evidence for guideline development.
  • Existing geriatric oncology guidelines exhibit variable methodological quality and applicability.

Purpose of the Study:

  • To evaluate the quality and clinical applicability of established geriatric oncology guidelines.
  • Utilized the Appraisal of Guidelines Research and Evaluation II (AGREE II) instrument for assessment.

Main Methods:

  • Conducted a systematic literature search across major databases and oncology society websites.
  • Included guidelines published from 2000-2025, focusing on cancer care in older adults with documented methodologies.
  • Appraised 6 selected guidelines using the AGREE II tool across six domains by two independent reviewers.

Main Results:

  • Identified 6 eligible guidelines from 807 records.
  • Guidelines generally scored high in clarity and scope but low in stakeholder involvement and applicability.
  • Recent ASCO guidelines showed higher methodological rigor compared to others lacking comprehensive evidence synthesis and user applicability.

Conclusions:

  • Geriatric oncology guidelines show acceptable quality but have inconsistencies in stakeholder engagement and practical implementation.
  • Enhanced methodological rigor and inclusive development are crucial for improving future guidelines.
  • Effective translation of guidelines into geriatric oncology practice requires addressing these limitations.