Related Experiment Video
Updated: May 5, 2026

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
Published on: November 13, 2016
Imaging Methods for New-Onset Seizures at Canadian Pediatric Hospitals.
Kate Hurley1, Ellen Song1, Lucia Carpineta2,3
1Division of Neurology, Children's Hospital of Eastern Ontario, Research Institute, Faculty of Medicine, University of Ottawa, ON, Canada.
Pediatric neuroimaging for new-onset seizures shows wide practice variations in Canada. Guidelines are needed to standardize magnetic resonance imaging (MRI) protocols and reduce sedation use for children.
Area of Science:
- Pediatric Neurology
- Neuroradiology
- Medical Imaging
Background:
- Seizures are common in children, necessitating neuroimaging for diagnosis.
- Magnetic resonance imaging (MRI) is preferred over computed tomography (CT) for pediatric seizure evaluation due to superior sensitivity and absence of ionizing radiation.
- Current practices for pediatric seizure imaging protocols and sedation in Canada lack national guidelines.
Purpose of the Study:
- To assess current neuroimaging practices for pediatric new-onset seizures across Canadian tertiary pediatric centers.
- To evaluate the use of dedicated seizure MRI protocols, sedation, and non-sedated MRI techniques.
Main Methods:
- A cross-sectional survey was distributed to radiologists at 16 Canadian tertiary pediatric centers.
- The survey collected data on MRI protocols for new-onset seizures, sedation practices, and strategies for non-sedated MRI.
- Response rate was 94% (15 centers).
Main Results:
- Significant variability in MRI protocols was observed; only 13% used dedicated new-onset seizure protocols, while 67% used epilepsy-specific protocols.
- Sedation practices varied widely, with a median sedation age range from 3 months to 6 years.
- Non-sedated techniques like feed-and-swaddle (93%) and natural sleep (27%) were common in infants; video goggles (67%) and child life support (53%) aided older children.
Conclusions:
- Substantial heterogeneity exists in MRI protocols and sedation use for pediatric new-onset seizures across Canadian centers.
- The findings highlight an urgent need for national consensus guidelines to standardize imaging, minimize sedation, and improve patient care.
- Standardization could enhance diagnostic accuracy and patient experience in pediatric seizure management.
More Related Videos
10:22Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
Published on: December 6, 2016
09:57Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
Published on: September 20, 2024