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Monitoring PD-1-Blocking Antibodies Bound to T Cells Derived from a Drop of Peripheral Blood
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[Side effects of immune checkpoint inhibitors : Focus on pulmonary events]

Alexey Surov1, Jan Borggrefe2

  • 1Institut für Radiologie, Neuroradiologie und Nuklearmedizin, Ruhr-Universität Bochum, Johannes-Wesling Klinikum, Minden, Hans-Nolte-Str. 1, 32429, Minden, Deutschland. Alexey.Surov@muehlenkreiskliniken.de.

Radiologie (Heidelberg, Germany)
|December 16, 2025
PubMed

The development of immune checkpoint inhibitors (ICI) has revolutionized cancer treatment. ICI enhance antitumor immunity by inhibiting the negative regulatory components of the T cell-mediated immune response against tumor cells. ICI are associated with less toxicity in comparison compared to chemotherapy. However, immune-mediated adverse events (iAEs) may occur during therapy with ICI. This paper focuses on pulmonary iAEs events in therapy with ICI.

Keywords:
Computed tomographyImmune-related adverse eventsImmunotherapyPneumonitisSarcoidosis

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