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Pulmonary Nodular Lymphoid Hyperplasia: Reviewing a Lung Cancer Mimicker
Gabriela Schneider Galvão1, Jônatas Fávero Prietto Dos Santos1, Ying-Han R Hsu2
1Joint Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.
Lung Cancer (Auckland, N.Z.)
|December 17, 2025
Summary
Pulmonary nodular lymphoid hyperplasia is a rare lung condition that can mimic cancer. Diagnosis requires histopathology, but this benign disorder may resolve spontaneously, as seen in a recent case.
Area of Science:
- Pulmonology
- Pathology
- Radiology
Background:
- Pulmonary nodular lymphoid hyperplasia (PNLH) is a rare, benign lymphoproliferative disorder.
- Patients are often asymptomatic, with radiological findings including peripheral nodules or mass-like consolidation.
- PNLH can mimic more common lung diseases like lung cancer and lymphoma, leading to diagnostic delays.
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