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Updated: Jan 8, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Choroidal Metastasis of a Cutaneous Melanoma: A Case Report
Jacky Jiang1, Ebrar Al-Yasery2, Jackson Chee Chea Lee2
1University of New South Wales, Sydney, NSW, Australia.
Introduction:
We report the clinical, imaging, histopathological, and genetic features of a choroidal metastasis originating from a cutaneous melanoma.
Case Presentation:
A 92-year-old woman presented with an asymptomatic pigmented lesion in her right eye. She had a history of prior cutaneous melanoma. Workup revealed widespread metastases to the liver, lungs, and brain. Histopathology (post-mortem eye) showed melanoma cells of the epithelioid cell type. Genetic analysis was positive for the BRAF V600K variant, confirming the cutaneous origin of the choroidal tumour.
Conclusion:
Choroidal metastasis of a cutaneous melanoma is a rare manifestation that can be mistaken for a primary choroidal melanoma. A comprehensive clinical history, histopathology, and genetic analysis are useful in distinguishing between the two entities.

